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The sixth angel poured out his bowl on the great river Euphrates, and its water was dried up to prepare the way for the kings from the East. Revelation 16:12 The sixth angel sounded his trumpet, and I heard a voice coming from the four horns of the golden altar that is before God. It said to the sixth angel who had the trumpet, “Release the four angels who are bound at the great river Euphrates.” Revelation 9:13 & 14