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The NHLBI has been conducting research for 75 years, making a significant impact through studies, clinical research, health education, and dissemination. It was founded in 1948 as the National Health Institute, and its initial work, such as the Framingham Heart Study, continues to have an impact today. For over 75 years, NHLBI has funded and conducted research that's helped millions, from groundbreaking epidemiological studies and clinical research, to innovations in health education and dissemination. The story begins in 1948, when NHLBI was founded as the National Health Institute. And that initial work, like the Framingham Heart Study, is still making an impact today.