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Virtual patient data—digital twins, synthetic datasets, and in-silico trials—offers transformative potential for paediatric clinical research by addressing low enrolment and inadequate statistical power. These digital health innovations promise faster, cost-effective, safer trials whilst requiring robust ethical frameworks for data privacy and consent. Integration could enhance research quality and efficiency, though limitations include unpredictable adverse events and placebo effects.
Comment
Virtual patient data—digital twins, synthetic datasets, and in-silico trials—offers transformative potential for paediatric clinical research by addressing low enrolment and inadequate statistical power. These digital health innovations promise faster, cost-effective, safer trials whilst requiring robust ethical frameworks for data privacy and consent. Integration could enhance research quality and efficiency, though limitations include unpredictable adverse events and placebo effects.
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