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Virtual patient data—digital twins, synthetic datasets, and in-silico trials—offers transformative potential for paediatric clinical research by addressing low enrolment and inadequate statistical power. These digital health innovations promise faster, cost-effective, safer trials whilst requiring robust ethical frameworks for data privacy and consent. Integration could enhance research quality and efficiency, though limitations include unpredictable adverse events and placebo effects.
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Virtual patient data—digital twins, synthetic datasets, and in-silico trials—offers transformative potential for paediatric clinical research by addressing low enrolment and inadequate statistical power. These digital health innovations promise faster, cost-effective, safer trials whilst requiring robust ethical frameworks for data privacy and consent. Integration could enhance research quality and efficiency, though limitations include unpredictable adverse events and placebo effects.
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